Helmbrecht, T. O., dal Maschio, M., Donovan, J. C., Koutsouli, S., & Baier, H. (2018). Topography of a Visuomotor Transformation. Neuron.
In ZF, two distinct pathways from OT to HB: one for prey, another for avoidance. Rev: damage to OT prevents orienting towards prey. Optogenetics: stimulate diff neurons in the OT, detect motor outputs. Clustering: 2 distinct behav: escapes and approaches. Moreover, retinotopic position and eye position are integrated, to calculate the maneuver. Combined with whole-brain gcamp img, observed targeted HB neurons activated. Then traced individ neurons and classified into 8 classes, based on projection targets, including ipsi- and contra- to HB, several distinct type of commissural, etc. Up-down retinotopy is less precisely encoded than LR (aka rostro-caudal).
In ZF, two distinct pathways from OT to HB: one for prey, another for avoidance. Rev: damage to OT prevents orienting towards prey. Optogenetics: stimulate diff neurons in the OT, detect motor outputs. Clustering: 2 distinct behav: escapes and approaches. Moreover, retinotopic position and eye position are integrated, to calculate the maneuver. Combined with whole-brain gcamp img, observed targeted HB neurons activated. Then traced individ neurons and classified into 8 classes, based on projection targets, including ipsi- and contra- to HB, several distinct type of commissural, etc. Up-down retinotopy is less precisely encoded than LR (aka rostro-caudal).